Get firmer, more radiant skin: Ways to outsmart 'zombie cells' that speed up skin ageing

The term “zombie cells” may conjure up gruesome images of the undead from your favourite horror movie, but this nickname refers to a phenomenon that causes our skin to age.

These cells, scientifically known as senescent cells, not only lose their vitality and functionality but also wreak havoc on the surrounding healthy cells. This sinister process creates a domino effect, accelerating the skin-ageing process throughout your entire complexion.

The outcome is skin that is dull and lacklustre. It's fitting, then, that these disruptive elements have been labelled "zombie cells"; like a relentless plague, they spread their degenerative effects, stealthily eroding your skin’s vibrant radiance.

As we age, research has shown that the breakdown of major skin mechanisms leads to slower cell renewal and loss of hyaluronic acid in skin, which leads to the emergence of fine lines or wrinkles, dullness, and loose or sagging skin.  

Targeting ageing cells at their source

With this in mind, Eau Thermale Avène set out to create targeted skincare that focuses on the behaviour of these senescent cells. 

Says the brand’s managing director Anne-Laure Nguyen Huy Lai: “Our research and development teams worked for six years with the world specialist in ageing, Professor Jean-Marc Lemaitre, research director at Inserm, co-director of the Institute for Regenerative Medicine and Biotherapy.”

Through intensive research, they discovered that by combining two key active ingredients – hyaluronic acid and concentrated niacinamide – it was possible to target these “zombie cells” to help slow down the ageing process in the long term.

This is because niacinamide, or vitamin B3, plays an essential role in reinforcing the skin’s natural barrier, boosting collagen production to improve skin elasticity and fighting off fine lines. Hyaluronic acid, in turn, provides crucial hydration that allows for plumper and smoother-looking skin.

The result? A game-changing range of skincare that has a direct effect on cellular senescence, or the root cause of skin ageing, instead of only fighting off the visible signs when they occur.

An innovative hybrid skincare formula 

At the heart of Avène’s Hyaluron Activ B3 skincare line-up, the Cell Renewal Aqua Cream-in-Gel, $79.90 (50 ml), stands out for its revitalising and multi-tasking properties. 

This potent formula is packed with powerhouse ingredients, featuring an impressive concentration of six per cent niacinamide, alongside hyaluronic acid and avocado oil to restore your skin’s glow. 

What makes this hydrator effective against “zombie cells” is the high concentration of niacinamide, which has been shown to extend cell longevity by 50 per cent¹. Additionally, it features a low molecular weight hyaluronic acid, which penetrates more deeply to target senescent cells, thus rehydrating your skin² and filling in wrinkles. 

Boasting a lightweight texture, this special formulation is ideal for our tropical climate, so your skin stays hydrated with no sticky or heavy afterfeel.

This means it’s versatile for use as a day cream, night cream or even a mask. Its uplifting fragrance – a tranquil blend of bamboo water and red apple sorbet, with notes of lotus, peony and magnolia – also makes it a great mood booster. 

Complete your skincare regimen with the Hyaluron Activ B3 range

Keen to build a complete skin routine that battles “zombie cells”? Experience the full benefits with the Hyaluron Activ B3 face care range, which also includes the following:

• Concentrated Plumping Serum, $88.90 (30ml)
  Target fine lines with a fragrance-free serum that’s gentle enough even for sensitive skin.
• Triple Correction Eye Cream, $69.90 (15ml)
  This gel-cream formulation helps improve the look of dark circles and restores eye radiance. 
• Multi-Intensive Night Cream, $91.90 (40ml)
  Revitalise your skin overnight with this retinal-rich yet non-oily cream.

The Hyaluron Activ B3 range is available at Watsons and Guardian.

¹ Activité anti-âge – H. T. Kang et al., Aging Cell (2006) 5, pp. 423-436. 
² Prof. Saurat, 2013, Reports HA120SelsGK231013 and HA120GK231013.